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Stick With It: Why Maintenance Matters for Weight Loss Success

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After months (or maybe even years) of hard work, the scale hits your goal weight and the moment you’ve been waiting for has arrived. Reaching your goal weight is a HUGE deal and an amazing accomplishment, but it may feel less like crossing a finish line than you think. 

As more and more people discover success through weight loss medications, more and more people are entering what is known as the maintenance phase of weight loss. 

Welcome to the Maintenance Phase
You’ve probably already mastered the basics of weight loss, like eating a healthy diet, increasing physical activity, and building healthier habits. However, maintaining weight loss requires a new mindset—one that focuses on sustaining those habits for the long term. 

The maintenance phase is about finding a balance between enjoying life and staying mindful of your health. It’s no longer about aggressively losing pounds but instead about keeping the weight off via a sustainable, healthy lifestyle.

This may mean new challenges to overcome. Some people experience anxiety about regaining weight, while others may feel a bit lost without the clear structure of a weight loss goal. It’s crucial to recognize that maintenance is about health, balance, and finding a sense of normalcy. Be kind to yourself as you adapt to this new phase.

How to Stay on Track, Long-Term
The good news? You’re not starting from scratch with the maintenance phase. The habits and discipline that helped you lose weight will be your biggest allies for long-term success:

  1. Continue to document your journey
    While you may not need to weigh yourself every single day, regular check-ins can help you stay mindful of your progress. This could be checking your fitness wearable data once a week, seeing how your clothes are fitting, or even just keeping note of how you feel overall. Monitoring keeps you accountable without putting too much pressure on the numbers.

  2. Prioritize movement
    Exercise is not just for weight loss—it’s essential for maintaining your health over time and as you age. Find activities you enjoy so that movement becomes a fun and rewarding part of your routine. Whether it’s going for walks, lifting weights, or joining a group fitness class, the key is consistency.

  3. Practice mindful eating
    Mindful eating (paying attention to your hunger and fullness cues) is still important. Enjoying the occasional treat is fine, but continue to choose whole foods, practice portion control, and be aware of any cravings that may appear.

  4. Embrace community and support
    Having a support system in place is key to staying on track. Whether it’s a friend on a similar journey, a weight loss support group, or a social media community, connecting with others who understand what you’re going through can provide motivation and accountability through the maintenance phase and beyond.

  5. Understand small weight fluctuations are normal
    Your weight can shift slightly, thanks to natural things like water retention, hormones, or even how much fiber you ate the day before. Don’t panic. Instead, focus on overall trends over time—consider weekly or bi-weekly weigh-ins. If you notice consistent weight gain, that’s your cue to reassess your habits or talk to your provider.

  6. Team up with your care team
    Continuing regular appointments with your healthcare providers is important even after you reach your goal weight. Not only will they monitor your long-term health, but they can also provide suggestions on how to tweak your lifestyle habits during the maintenance phase. You can also continue your relationships with nutritionists, therapists, and other auxiliary providers you’ve worked with on your journey.

Remember: the maintenance phase is not about being perfect, but about finding a healthy, sustainable lifestyle that works for you. It’s natural to have ups and downs along the way, but with the right mindset and support, you can stay on track and maintain your incredible progress.

And don't forget to give yourself some credit for how far you've come! Every day is another chance to do it right—you got this.

CON-2208-001 10/24
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Important Safety Information
What is CONTRAVE?
See More 

CONTRAVE can cause serious side effects including:

Suicidal thoughts or actions: One of the ingredients in CONTRAVE is bupropion. Bupropion has caused some people to have suicidal thoughts or actions or unusual changes in behavior, whether or not they are taking medicines used to treat depression. Bupropion may increase the risk of suicidal thoughts or actions in some children, teenagers, and young adults within the first few months of treatment. If you already have depression or other mental illnesses, taking bupropion may cause it to get worse, especially within the first few months of treatment.

CONTRAVE is a prescription weight-loss medicine that may help some adults with a body mass index (BMI) of 30 kg/m2 or greater (obese), or adults with a BMI of 27 kg/m2 or greater (overweight) with at least one weight-related medical problem such as high blood pressure, high cholesterol, or type 2 diabetes, lose weight and keep the weight off.

Important Safety Information
See More
CONTRAVE can cause serious side effects including:
Suicidal thoughts or actions: One of the ingredients in CONTRAVE is bupropion. Bupropion has caused some people to have suicidal thoughts or actions or unusual changes in behavior, whether or not they are taking medicines used to treat depression. Bupropion may increase the risk of suicidal thoughts or actions in some children, teenagers, and young adults within the first few months of treatment. If you already have depression or other mental illnesses, taking bupropion may cause it to get worse, especially within the first few months of treatment.
What is CONTRAVE?
See More
CONTRAVE is indicated as an adjunct to a reduced-calorie diet and increased physical activity for chronic weight management in adults with an initial body mass index (BMI) of:
Important Safety Information
What is CONTRAVE?
See Less 

CONTRAVE can cause serious side effects including:

Suicidal thoughts or actions: One of the ingredients in CONTRAVE is bupropion. Bupropion has caused some people to have suicidal thoughts or actions or unusual changes in behavior, whether or not they are taking medicines used to treat depression. Bupropion may increase the risk of suicidal thoughts or actions in some children, teenagers, and young adults within the first few months of treatment. If you already have depression or other mental illnesses, taking bupropion may cause it to get worse, especially within the first few months of treatment.

While taking CONTRAVE, you or your family members should pay close attention to any changes, especially sudden changes, in mood, behaviors, thoughts, or feelings. This is very important when you start taking CONTRAVE or when your dose changes.

Stop taking CONTRAVE and call a healthcare provider right away if you or your family members notice any of the following symptoms, especially if they are new, worse, or worry you: thoughts about suicide or dying; attempts to commit suicide; depression; anxiety; feeling agitated or restless; panic attacks; irritability; aggression, anger, or violence; acting on dangerous impulses; an extreme increase in activity and talking; other unusual changes in behavior or mood; trouble sleeping.

CONTRAVE is not approved for use in children under the age of 18.

Do not take CONTRAVE if you have uncontrolled high blood pressure; have or have had seizures; use other medicines that contain bupropion such as WELLBUTRIN, WELLBUTRIN SR, WELLBUTRIN XL, APLENZIN and ZYBAN; have or have had an eating disorder called anorexia or bulimia; are dependent on opioid pain medicines or use medicines to help stop taking opioids, or are in opiate withdrawal; drink a lot of alcohol and abruptly stop drinking, or use medicines called sedatives (these make you sleepy), benzodiazepines, or anti‐seizure medicines and stop using them all of a sudden; are taking or have taken medicines called monoamine oxidase inhibitors (MAOIs) in the past 14 days; or are allergic to any of the ingredients in CONTRAVE.

Tell your healthcare provider about all of your medical conditions, including if you have: depression or other mental illnesses; attempted suicide; seizures; head injury; tumor or infection of brain or spine; low blood sugar or low sodium; liver or kidney problems; high blood pressure; heart attack, heart problems, or stroke; eating disorder; drinking a lot of alcohol; prescription medicine or street drug abuse; are 65 or older; diabetes; pregnant or planning to become pregnant; or breastfeeding.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

CONTRAVE may cause serious side effects, including:

  • Seizures. There is a risk of having a seizure when you take CONTRAVE. The risk of seizure is higher in people who take higher doses of CONTRAVE, have certain medical conditions, or take CONTRAVE with certain other medicines. Do not take any other medicines while you are taking CONTRAVE unless your healthcare provider has said it is okay to take them. If you have a seizure while taking CONTRAVE, stop taking CONTRAVE and call your healthcare provider right away.

  • Risk of opioid overdose. Do not take large amounts of opioids, including opioid-containing medicines, such as heroin or prescription pain pills, to try to overcome the opioid-blocking effects of naltrexone. This can lead to serious injury, coma, or death.

    Get emergency medical help right away if you take opioids and you:

    • have trouble breathing

    • become very drowsy with slowed breathing

    • have slow, shallow breathing

    • feel faint, very dizzy, confused, or have unusual symptoms

  • Sudden opioid withdrawal. People who take CONTRAVE must not use any type of opioid, including street drugs, prescription pain medicines, cough, cold, or diarrhea medicines that contain opioids, or opioid dependence treatments, for at least 7 to 10 days before starting CONTRAVE. Using opioids in the 7 to 10 days before you start taking CONTRAVE may cause you to suddenly have symptoms of opioid withdrawal when you take it. Sudden opioid withdrawal can be severe, and you may need to go to the hospital. Tell your healthcare provider you are taking CONTRAVE before a medical procedure or surgery.

  • Severe allergic reactions. Stop taking CONTRAVE and call your healthcare provider or go to the nearest hospital emergency room right away if you have any of the following signs and symptoms of an allergic reaction: rash, itching, hives, fever, swollen lymph glands, painful sores in your mouth or around your eyes, swelling of your lips or tongue, chest pain, or trouble breathing.

  • Increases in blood pressure or heart rate. Some people may get high blood pressure or have a higher heart rate when taking CONTRAVE. Your healthcare provider should check your blood pressure and heart rate before you start taking, and while you take CONTRAVE.

  • Liver damage or hepatitis. Stop taking CONTRAVE and tell your healthcare provider if you have any of the following symptoms of liver problems: stomach area pain lasting more than a few days, dark urine, yellowing of the whites of your eyes, or tiredness. Your healthcare provider may need to stop treating you with CONTRAVE if you get signs or symptoms of a serious liver problem.

  • Manic episodes. Bupropion can cause some people who were manic or depressed in the past to become manic or depressed again.

  • Visual problems (angle-closure glaucoma). Signs and symptoms may include: eye pain, changes in vision, swelling or redness in or around the eye. Talk with your healthcare provider to find out if you are at risk for angle‐closure glaucoma and to get treatment to prevent it if you are at risk.

  • Increased risk of low blood sugar in people with type 2 diabetes mellitus who also take medicines to treat their diabetes (such as insulin or sulfonylureas). You should check your blood sugar before you start taking CONTRAVE and while you take CONTRAVE.

The most common side effects of CONTRAVE include nausea, constipation, headache, vomiting, dizziness, trouble sleeping, dry mouth, and diarrhea. These are not all of the possible side effects of CONTRAVE.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

What is CONTRAVE?

CONTRAVE is a prescription weight-loss medicine that may help some adults with a body mass index (BMI) of 30 kg/m2 or greater (obese), or adults with a BMI of 27 kg/m2 or greater (overweight) with at least one weight-related medical problem such as high blood pressure, high cholesterol, or type 2 diabetes, lose weight and keep the weight off.

CONTRAVE should be used with a reduced-calorie diet and increased physical activity.

It is not known if CONTRAVE changes your risk of heart problems or stroke or of death due to heart problems or stroke.

It is not known if CONTRAVE is safe and effective when taken with other prescription, over-the-counter, or herbal weight-loss products.

CONTRAVE is not approved to treat depression or other mental illnesses, or to help people quit smoking (smoking cessation).

Please see Full Prescribing Information, including Medication Guide, for CONTRAVE.