--- title: Healthy Lifestyle & Weight Loss Blog | CONTRAVE® (naltrexone HCI/bupropion HCI) description: Improve your knowledge on weight loss through Lifestyle, Exercise, and Nutrition resources and tips from CONTRAVE® (naltrexone HCI/bupropion HCI) to support your weight loss journey. --- - [Prescribing Information](https://www.curraxpharma.com/PI/contrave-label-current.pdf) - [Medication Guide](https://www.curraxpharma.com/MG/contrave-label-current.pdf) - [Healthcare Providers](https://contravehcp.com/) - [ABOUT CONTRAVE](https://contrave.com/about/) - [What is CONTRAVE?](https://contrave.com/about/) - [How CONTRAVE works](https://contrave.com/how-contrave-works/) - [Results with CONTRAVE](https://contrave.com/results/) - [WHAT TO EXPECT](https://contrave.com/what-to-expect/) - [SUCCESS STORIES](https://contrave.com/success-stories/) - CONTRAVE RESOURCES - [The CONTRAVE Chronicles Blog](https://blog.contrave.com/) - [Talking about CONTRAVE](https://contrave.com/get-started/) - [Physician finder](https://doctors.contrave.com/) - [Resource center](https://contrave.com/resources/) - [FAQS](https://contrave.com/faqs/) - [2 Ways To Save](https://contrave.com/save/) - [TALK TO A DOCTOR ONLINE](https://contrave.com/?modal=talk-to-doctor) [![Contrave logo](https://blog.contrave.com/hs-fs/hubfs/raw_assets/public/Contrave_2_OG/images/LogoHCI.png?width=200&name=LogoHCI.png "Contrave logo")](https://contrave.com/) [Talk to a DOCTOR ONLINE](https://contrave.com/?modal=talk-to-doctor) - [ABOUT CONTRAVE](https://contrave.com/about/) - [What is CONTRAVE?](https://contrave.com/about/) - [How CONTRAVE works](https://contrave.com/how-contrave-works/) - [Results with CONTRAVE](https://contrave.com/results/) - [WHAT TO EXPECT](https://contrave.com/what-to-expect/) - [SUCCESS STORIES](https://contrave.com/success-stories/) - CONTRAVE RESOURCES - [The CONTRAVE Chronicles Blog](https://blog.contrave.com/) - [Talking about CONTRAVE](https://contrave.com/get-started/) - [Physician finder](https://doctors.contrave.com/) - [Resource center](https://contrave.com/resources/) - [FAQS](https://contrave.com/faqs/) - [2 Ways To Save](https://contrave.com/save/) - [TALK TO A DOCTOR ONLINE](https://contrave.com/?modal=talk-to-doctor) --- - [Prescribing Information](https://www.curraxpharma.com/PI/contrave-label-current.pdf) - [Medication Guide](https://www.curraxpharma.com/MG/contrave-label-current.pdf) - [For healthcare providers](https://contrave.com/) - [ABOUT CONTRAVE](https://contrave.com/about/) - [What is CONTRAVE?](https://contrave.com/about/) - [How CONTRAVE works](https://contrave.com/how-contrave-works/) - [Results with CONTRAVE](https://contrave.com/results/) - [WHAT TO EXPECT](https://contrave.com/what-to-expect/) - [SUCCESS STORIES](https://contrave.com/success-stories/) - CONTRAVE RESOURCES - [The CONTRAVE Chronicles Blog](https://blog.contrave.com/) - [Talking about CONTRAVE](https://contrave.com/get-started/) - [Physician finder](https://doctors.contrave.com/) - [Resource center](https://contrave.com/resources/) - [FAQS](https://contrave.com/faqs/) - [2 Ways To Save](https://contrave.com/save/) - [TALK TO A DOCTOR ONLINE](https://contrave.com/?modal=talk-to-doctor) # The CONTRAVE Chronicles Blog Improve your knowledge about weight loss with resources and tips from CONTRAVE about lifestyle, exercise, and nutrition. Filter by topic: - [All](https://blog.contrave.com/) - [Advocacy](https://blog.contrave.com/tag/advocacy) - [Education](https://blog.contrave.com/tag/education) - [Exercise](https://blog.contrave.com/tag/exercise) - [Healthcare](https://blog.contrave.com/tag/healthcare) - [Individualized care](https://blog.contrave.com/tag/individualized-care) - [Lifestyle](https://blog.contrave.com/tag/lifestyle) - [Nutrition](https://blog.contrave.com/tag/nutrition) - [Recipes](https://blog.contrave.com/tag/recipes) - [Seasonal](https://blog.contrave.com/tag/seasonal) - [Self-Care](https://blog.contrave.com/tag/self-care) - [Success Stories](https://blog.contrave.com/tag/success-stories) - [Support](https://blog.contrave.com/tag/support) [Lifestyle](https://blog.contrave.com/tag/lifestyle), [Exercise](https://blog.contrave.com/tag/exercise), [Education](https://blog.contrave.com/tag/education) ## [Healthy Ways to Lose Fat—Not Muscle](https://blog.contrave.com/healthy-ways-to-lose-fat-not-muscle) When you step on the scale and see the number go down, it’s easy to assume that all weight loss... 2 minute read [Read More](https://blog.contrave.com/healthy-ways-to-lose-fat-not-muscle) [Lifestyle](https://blog.contrave.com/tag/lifestyle), [Education](https://blog.contrave.com/tag/education), [Individualized Care](https://blog.contrave.com/tag/individualized-care) ## [Trust Your Gut: Weight Loss and the Microbiome](https://blog.contrave.com/trus-your-gut-weight-loss-and-the-microbiome) When it comes to weight loss, diet and exercise usually take center stage, sometimes sharing... 2 minute read [Read More](https://blog.contrave.com/trus-your-gut-weight-loss-and-the-microbiome) [Lifestyle](https://blog.contrave.com/tag/lifestyle), [Exercise](https://blog.contrave.com/tag/exercise), [Education](https://blog.contrave.com/tag/education) ## [Water vs. Electrolytes: How Hydrated Is Enough?](https://blog.contrave.com/water-vs-electrolytes-how-hydrated-is-enough) Water seems to be very top of mind these days! It’s hard to go anywhere these days without... 2 minute read [Read More](https://blog.contrave.com/water-vs-electrolytes-how-hydrated-is-enough) [Healthcare](https://blog.contrave.com/tag/healthcare), [Support](https://blog.contrave.com/tag/support), [Education](https://blog.contrave.com/tag/education) ## [Stress Less With A Provider Visit Action Plan](https://blog.contrave.com/stress-less-with-a-provider-visit-plan) Navigating a provider appointment can sometimes feel overwhelming—especially when you’re... 2 minute read [Read More](https://blog.contrave.com/stress-less-with-a-provider-visit-plan) [Lifestyle](https://blog.contrave.com/tag/lifestyle), [Nutrition](https://blog.contrave.com/tag/nutrition), [Individualized Care](https://blog.contrave.com/tag/individualized-care) ## [Ask an RD: 6 Meal Planning and Prepping Hacks from an RD](https://blog.contrave.com/ask-an-rd-6-meal-planning-and-prepping-hacks-from-an-rd) Jessica Cording, RD, is a registered dietitian, health coach, and author with a passion for... 3 minute read [Read More](https://blog.contrave.com/ask-an-rd-6-meal-planning-and-prepping-hacks-from-an-rd) [Success Stories](https://blog.contrave.com/tag/success-stories), [Advocacy](https://blog.contrave.com/tag/advocacy) ## [Meet Vickie and How She Got Back on Her Horse](https://blog.contrave.com/meet-vickie-and-how-she-got-back-on-her-horse) I’m Vickie, 65, a retired medical professional living in the eastern deserts of Washington. I... 1 minute read [Read More](https://blog.contrave.com/meet-vickie-and-how-she-got-back-on-her-horse) [Lifestyle](https://blog.contrave.com/tag/lifestyle), [Education](https://blog.contrave.com/tag/education), [Advocacy](https://blog.contrave.com/tag/advocacy) ## [Food Noise vs Food Cravings: Understanding the Difference](https://blog.contrave.com/food-noise-vs-food-cravings-understanding-the-difference) One major obstacle to achieving weight loss goals can be how much someone thinks about food. 2 minute read [Read More](https://blog.contrave.com/food-noise-vs-food-cravings-understanding-the-difference) [Lifestyle](https://blog.contrave.com/tag/lifestyle), [Education](https://blog.contrave.com/tag/education), [Individualized Care](https://blog.contrave.com/tag/individualized-care) ## [Finding Your Why: The Reasons We Do This](https://blog.contrave.com/finding-your-why-the-reasons-we-do-this) The first step to losing weight and getting healthier is not buying a scale, signing up for a... 2 minute read [Read More](https://blog.contrave.com/finding-your-why-the-reasons-we-do-this) [Lifestyle](https://blog.contrave.com/tag/lifestyle), [Support](https://blog.contrave.com/tag/support), [Education](https://blog.contrave.com/tag/education) ## [How to Keep Your Motivation Going All Year Long](https://blog.contrave.com/how-to-keep-your-motivation-going-all-year-long) Sticking to your weight and health goals can feel easier in January when motivation is high... 3 minute read [Read More](https://blog.contrave.com/how-to-keep-your-motivation-going-all-year-long) [Healthcare](https://blog.contrave.com/tag/healthcare), [Education](https://blog.contrave.com/tag/education) ## [What Are Compounded Medications?](https://blog.contrave.com/what-are-compounded-medications) What happens when a medicine you’re prescribed and taking regularly isn’t available anymore?Not... 2 minute read [Read More](https://blog.contrave.com/what-are-compounded-medications) Important Safety Information What is CONTRAVE? See More  ### CONTRAVE can cause serious side effects including: Suicidal thoughts or actions: One of the ingredients in CONTRAVE is bupropion. Bupropion has caused some people to have suicidal thoughts or actions or unusual changes in behavior, whether or not they are taking medicines used to treat depression. Bupropion may increase the risk of suicidal thoughts or actions in some children, teenagers, and young adults within the first few months of treatment. If you already have depression or other mental illnesses, taking bupropion may cause it to get worse, especially within the first few months of treatment. CONTRAVE is a prescription weight-loss medicine that may help adults with obesity, or some adults who are overweight who also have weight-related medical problems, to lose excess body weight and keep the weight off. Important Safety Information and Indication See More **CONTRAVE can cause serious side effects including:** **Suicidal thoughts or actions:** One of the ingredients in CONTRAVE is bupropion. Bupropion has caused some people to have suicidal thoughts or actions or unusual changes in behavior, whether or not they are taking medicines used to treat depression. Bupropion may increase the risk of suicidal thoughts or actions in some children, teenagers, and young adults within the first few months of treatment. If you already have depression or other mental illnesses, taking bupropion may cause it to get worse, especially within the first few months of treatment. What is CONTRAVE? See More CONTRAVE is indicated as an adjunct to a reduced-calorie diet and increased physical activity for chronic weight management in adults with an initial body mass index (BMI) of: Important Safety Information and Indication What is CONTRAVE? See Less  ### CONTRAVE can cause serious side effects including: Suicidal thoughts or actions: One of the ingredients in CONTRAVE is bupropion. Bupropion has caused some people to have suicidal thoughts or actions or unusual changes in behavior, whether or not they are taking medicines used to treat depression. Bupropion may increase the risk of suicidal thoughts or actions in some children, teenagers, and young adults within the first few months of treatment. If you already have depression or other mental illnesses, taking bupropion may cause it to get worse, especially within the first few months of treatment. While taking CONTRAVE, you or your family members should pay close attention to any changes, especially sudden changes, in mood, behaviors, thoughts, or feelings. This is very important when you start taking CONTRAVE or when your dose changes. Stop taking CONTRAVE and call a healthcare provider right away if you or your family members notice any of the following symptoms, especially if they are new, worse, or worry you: thoughts about suicide or dying; attempts to commit suicide; depression; anxiety; feeling agitated or restless; panic attacks; irritability; aggression, anger, or violence; acting on dangerous impulses; an extreme increase in activity and talking; other unusual changes in behavior or mood; trouble sleeping. CONTRAVE is not approved for use in children under the age of 18. Do not take CONTRAVE if you have uncontrolled high blood pressure; have or have had seizures; use other medicines that contain bupropion such as WELLBUTRIN, WELLBUTRIN SR, WELLBUTRIN XL, APLENZIN and ZYBAN; have or have had an eating disorder called anorexia or bulimia; are dependent on opioid pain medicines or use medicines to help stop taking opioids, or are in opiate withdrawal; drink a lot of alcohol and abruptly stop drinking, or use medicines called sedatives (these make you sleepy), benzodiazepines, or anti‐seizure medicines and stop using them all of a sudden; are taking or have taken medicines called monoamine oxidase inhibitors (MAOIs) in the past 14 days; or are allergic to any of the ingredients in CONTRAVE. Tell your healthcare provider about all of your medical conditions, including if you have: depression or other mental illnesses; attempted suicide; seizures; head injury; tumor or infection of brain or spine; low blood sugar or low sodium; liver or kidney problems; high blood pressure; heart attack, heart problems, or stroke; eating disorder; drinking a lot of alcohol; prescription medicine or street drug abuse; are 65 or older; diabetes; pregnant or planning to become pregnant; or breastfeeding. Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. ### CONTRAVE may cause serious side effects, including: - Seizures. There is a risk of having a seizure when you take CONTRAVE. The risk of seizure is higher in people who take higher doses of CONTRAVE, have certain medical conditions, or take CONTRAVE with certain other medicines. Do not take any other medicines while you are taking CONTRAVE unless your healthcare provider has said it is okay to take them. If you have a seizure while taking CONTRAVE, stop taking CONTRAVE and call your healthcare provider right away. - Risk of opioid overdose. Do not take large amounts of opioids, including opioid-containing medicines, such as heroin or prescription pain pills, to try to overcome the opioid-blocking effects of naltrexone. This can lead to serious injury, coma, or death. Get emergency medical help right away if you take opioids and you: - have trouble breathing - become very drowsy with slowed breathing - have slow, shallow breathing - feel faint, very dizzy, confused, or have unusual symptoms - Sudden opioid withdrawal. People who take CONTRAVE must not use any type of opioid, including street drugs, prescription pain medicines, cough, cold, or diarrhea medicines that contain opioids, or opioid dependence treatments, for at least 7 to 10 days before starting CONTRAVE. Using opioids in the 7 to 10 days before you start taking CONTRAVE may cause you to suddenly have symptoms of opioid withdrawal when you take it. Sudden opioid withdrawal can be severe, and you may need to go to the hospital. Tell your healthcare provider you are taking CONTRAVE before a medical procedure or surgery. - Severe allergic reactions. Stop taking CONTRAVE and call your healthcare provider or go to the nearest hospital emergency room right away if you have any of the following signs and symptoms of an allergic reaction: rash, itching, hives, fever, swollen lymph glands, painful sores in your mouth or around your eyes, swelling of your lips or tongue, chest pain, or trouble breathing. - Increases in blood pressure or heart rate. Some people may get high blood pressure or have a higher heart rate when taking CONTRAVE. Your healthcare provider should check your blood pressure and heart rate before you start taking, and while you take CONTRAVE. - Liver damage or hepatitis. Stop taking CONTRAVE and tell your healthcare provider if you have any of the following symptoms of liver problems: stomach area pain lasting more than a few days, dark urine, yellowing of the whites of your eyes, or tiredness. Your healthcare provider may need to stop treating you with CONTRAVE if you get signs or symptoms of a serious liver problem. - Manic episodes. Bupropion can cause some people who were manic or depressed in the past to become manic or depressed again. - Visual problems (angle-closure glaucoma). Signs and symptoms may include: eye pain, changes in vision, swelling or redness in or around the eye. Talk with your healthcare provider to find out if you are at risk for angle‐closure glaucoma and to get treatment to prevent it if you are at risk. - Increased risk of low blood sugar in people with type 2 diabetes mellitus who also take medicines to treat their diabetes (such as insulin or sulfonylureas). You should check your blood sugar before you start taking CONTRAVE and while you take CONTRAVE. The most common side effects of CONTRAVE include nausea, constipation, headache, vomiting, dizziness, trouble sleeping, dry mouth, and diarrhea. These are not all of the possible side effects of CONTRAVE. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit [www.fda.gov/medwatch](https://www.fda.gov/medwatch) or call [1-800-FDA-1088](tel:+18003321088). ### What is CONTRAVE? CONTRAVE is a prescription weight-loss medicine that may help adults with obesity, or some adults who are overweight who also have weight-related medical problems, to lose excess body weight and keep the weight off. CONTRAVE should be used with a reduced-calorie diet and increased physical activity. It is not known if CONTRAVE changes your risk of heart problems or stroke or of death due to heart problems or stroke. CONTRAVE is not approved to treat depression or other mental illnesses, or to help people quit smoking (smoking cessation). Please see [Full Prescribing Information](https://www.curraxpharma.com/PI/contrave-label-current.pdf), including [Medication Guide](https://www.curraxpharma.com/MG/contrave-label-current.pdf/), for CONTRAVE. [![Currax Pharmaceuticals LLC Logo](https://blog.contrave.com/hubfs/raw_assets/public/Contrave_2_OG/images/Currax-logo.svg "Currax Pharmaceuticals LLC Logo")](http://www.curraxpharma.com/) This website—including the contents and claims—is intended only for residents of the United States ages 18 and over. CONTRAVE® and Get CONTRAVE Now® are registered trademarks of Currax Pharmaceuticals LLC. Trademarks, registered or otherwise, are the property of their respective owner(s). © 2025 Currax Pharmaceuticals LLC. 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